Certificates of Analysis are the proof-points that regulated materials—from food ingredients to APIs—meet promised specs, yet most companies still chase them through email, shared drives, and spreadsheets. This article explains what a CoA is, why industries like food, pharma, cosmetics, chemicals, and animal nutrition depend on it, and how manual handling drains hundreds of staff-hours while exposing firms to lost, expired, or incorrect documents. It then walks through an AI-powered workflow that ingests, splits, extracts, validates, stores, indexes, and proactively renews CoAs with > 99% accuracy—turning a compliance burden into a searchable quality asset. A real-world case study of a global chemical-food distributor shows 90+% touchless processing, 60% faster cycle times, and audit prep cut from two days to minutes. The UpBrains AI CoA Agent’s purpose-built models, no-code rules, lifecycle tracking, and human-friendly exception UI make it the market’s most complete CoA automation solution, inviting readers to book a live demo.